Electronic control of DNA-based nanoswitches and nanodevices
نویسندگان
چکیده
منابع مشابه
Electronic control of DNA-based nanoswitches and nanodevices.
Here we demonstrate that we can rationally and finely control the functionality of different DNA-based nanodevices and nanoswitches using electronic inputs. To demonstrate the versatility of our approach we have used here three different model DNA-based nanoswitches triggered by heavy metals and specific DNA sequences and a copper-responsive DNAzyme. To achieve electronic-induced control of the...
متن کاملElectronic control of DNA-based nanoswitches and nanodevices† †Electronic supplementary information (ESI) available: Experimental procedures. See DOI: 10.1039/c5sc03694a Click here for additional data file.
Here we demonstrate that we can rationally and finely control the functionality of different DNA-based nanodevices and nanoswitches using electronic inputs. To demonstrate the versatility of our approach we have used here three different model DNA-based nanoswitches triggered by heavy metals and specific DNA sequences and a copper-responsive DNAzyme. To achieve electronic-induced control of the...
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DNA-based switches are currently operated by manual solution-phase addition of 'set-strands'. We demonstrate another operation method-sterically inaccessible 'set-strands', released from a surface into solution by spatially controlled photocleavage. This technique will enable microarrays of set-strands to operate many DNA-based switches in self-contained computational and diagnostic devices.
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DNA nanotechnology takes advantage of the predictability of DNA interactions to build complex DNA-based functional nanoscale structures. However, when DNA functional and responsive units that are based on non-canonical DNA interactions are employed it becomes quite challenging to predict, understand and control their thermodynamics. In response to this limitation, here we demonstrate the use of...
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Molecular recognition, programmability, self-assembling capabilites and biocompatibility are unique features of DNA. The basic approach of DNA nanotechnology is to exploit these properties in order to fabricate novel materials and structures on the nanometer scale. This cumulative dissertation deals with three aspects of this young research area: fast analysis, autonomous control of functional ...
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ژورنال
عنوان ژورنال: Chem. Sci.
سال: 2016
ISSN: 2041-6520,2041-6539
DOI: 10.1039/c5sc03694a